Sebastian Pagel

mjlab. Isaac Lab API, powered by MuJoCo-Warp, for RL and robotics research

destovky-lila. Scala

odysseus. Self-hosted AI workspace.

ponytail. Makes your AI agent think like the laziest senior dev in the room. The best code is the code you never wrote.

py2Dmol. Jupyter Notebook

pi. AI agent toolkit: unified LLM API, agent loop, TUI, coding agent CLI

OpenHarness. "OpenHarness: Open Agent Harness with a Built-in Personal Agent--Ohmo!"

openinterpreter. A lightweight coding agent for open models like Deepseek, Kimi, and Qwen

LeKiwi. LeKiwi - Low-Cost Mobile Manipulator

populora. Implementation and explorations into PopuLoRA, Co-Evolving LLM Populations for Reasoning Self-Play

cmux. Open source Ghostty-based macOS terminal with vertical tabs and notifications for AI coding agents. Built for multitasking, organization, and programmability.

assemblytheorytools. A centralised set of tools for doing assembly theory calculations

ds4. DeepSeek 4 Flash and PRO local inference engine for Metal, CUDA and ROCm

mem0. Universal memory layer for AI Agents

abtop. Like htop, but for AI coding agents. Monitor Claude Code & Codex CLI sessions, tokens, context window, rate limits, and ports in real-time.

hermes-agent. The agent that grows with you

gbrain. Garry's Opinionated OpenClaw/Hermes Agent Brain

career-ops. Open-source AI job search: scan job portals, score listings A-F, tailor your CV, track applications — runs locally in your AI coding CLI (Claude Code, Gemini, Codex, OpenCode…)

tmux-powerkit. The Ultimate tmux Status Bar Framework

extrakto. extrakto for tmux - quickly select, copy/insert/complete text without a mouse

claw-code. An agent-managed museum exhibit, built in Rust with Gajae-Code / LazyCodex — developed and maintained with no human intervention.

rtk. CLI proxy that reduces LLM token consumption by 60-90% on common dev commands. Single Rust binary, zero dependencies

nautilus_trader. Production-grade Rust-native trading engine with deterministic event-driven architecture

zellij. A terminal workspace with batteries included

feynman. TypeScript

last30days-skill. AI agent skill that researches any topic across Reddit, X, YouTube, HN, Polymarket, and the web - then synthesizes a grounded summary

TorchCode. 🔥 LeetCode for PyTorch — practice implementing softmax, attention, GPT-2 and more from scratch with instant auto-grading. Jupyter-based, self-hosted or try online.

tome. 🔁 Interactive Script playbooks for your terminal with Vim/Neovim (and Tmux)

autoresearch. AI agents running research on single-GPU nanochat training automatically

agent-of-empires. Manage multiple Claude Code, OpenCode agents from either TUI or Web for easy access on mobile. Also supports Mistral Vibe, Codex CLI, Gemini CLI, Pi.dev, Copilot CLI, Factory Droid Coding.

grafeo. Grafeo is a pure-Rust, high-performance graph database that can be embedded as a library or run as a standalone database, with optional in-memory or persistent storage. Grafeo supports both LPG and RDF and all major query languages.

PaRoutes. Home of the PaRoutes framework for benchmarking multi-step retrosynthesis predictions.

skydiscover. AI-Driven Scientific and Algorithmic Discovery

gdu. Fast disk usage analyzer with console interface written in Go

hishtory. Your shell history: synced, queryable, and in context

substrate-scope-plot. Jupyter Notebook

flashoptim. Python

cli. GitHub’s official command line tool

crewAI. Framework for orchestrating role-playing, autonomous AI agents. By fostering collaborative intelligence, CrewAI empowers agents to work together seamlessly, tackling complex tasks.

openclaw. Your own personal AI assistant. Any OS. Any Platform. The lobster way. 🦞

polymarket-cli. Rust

clihub. Turn any MCP server into CLI

lazygit. simple terminal UI for git commands

acra. Python

arpeggio. Calculation of interatomic interactions in molecular structures

molassembler. Chemoinformatics toolkit with support for inorganic molecules

tmux-sessionizer. instructions on using tmux-sessionizer to make project workflow blazingly fast

cpptraj. Biomolecular simulation trajectory/data analysis.

loguru. Python logging made (stupidly) simple

tmux. 🧛🏻‍♂️ Dark theme for tmux

pytorch-frame. Tabular Deep Learning Library for PyTorch

build-your-own-x. Master programming by recreating your favorite technologies from scratch.

chemputation. Wolfram Language

rendercv. Resume builder for academics and engineers

dotfiles. My dotfiles about vscode, gnome, or other

Lean. Lean Algorithmic Trading Engine by QuantConnect (Python, C#)

nano-egg. Evolution Pretraining Fully in Int Formats

xLSTM-Mixer. Python

UEFib. No nonsense Fibonacci on UEFI

disco_rl. Accompanying code for "Discovering State-of-the-art Reinforcement Algorithms" Nature publication

es-at-scale. This repo contains the source code for the paper "Evolution Strategies at Scale: LLM Fine-Tuning Beyond Reinforcement Learning"

ReaSyn. ReaSyn is a model for predicting a molecule's synthesis pathway, reaction steps from building blocks to final product(s), using an encoder-decoder Transformer and a Chain-of-Reaction (CoR) notation.

spalt. C++

LatentFrag. Structure-based fragment identification in latent space

MIDAS. Molecular Intelligence & Design Articulated by Semantics

DrugFlow. Multi-domain Distribution Learning for De Novo Drug Design

PocketFlow. Pocket Flow: 100-line LLM framework. Let Agents build Agents!

trackio. A lightweight, local-first, and free experiment tracking library from Hugging Face 🤗

XLeRobot. XLeRobot: Practical Dual-Arm Mobile Home Robot for $660

teachopencadd. TeachOpenCADD: a teaching platform for computer-aided drug design (CADD) using open source packages and data

oddt. Open Drug Discovery Toolkit

molnca. Python

papers-for-molecular-design-using-DL. List of Molecular and Material design using Generative AI and Deep Learning

flow_matching. A PyTorch library for implementing flow matching algorithms, featuring continuous and discrete flow matching implementations. It includes practical examples for both text and image modalities.

GRPO-Zero. Implementing DeepSeek R1's GRPO algorithm from scratch

flowr. Python

torch-sim. Torch-native, batchable, atomistic simulations.

PandaDock. PandaDock: Physics based Molecular Docking with GNN Scoring

maize. A graph-based workflow manager for computational chemistry pipelines

cheminfo_tutorial_20241028_pub. Jupyter Notebook

Rxn-INSIGHT. Analyzing chemical databases and predicting reaction conditions with cheminformatics

accelerated-computing-hub. NVIDIA curated collection of educational resources related to general purpose GPU programming.

exmol. Explainer for black box models that predict molecule properties

PufferLib. Puffing up reinforcement learning

smolagents. 🤗 smolagents: a barebones library for agents that think in code.

agency-swarm. Reliable Multi-Agent Orchestration Framework

llama.cpp. LLM inference in C/C++

Hunyuan3D-2. High-Resolution 3D Assets Generation with Large Scale Hunyuan3D Diffusion Models.

copier. Library and command-line utility for rendering projects templates.

PMDM. Python

assemblyphysics. Mathematica

zig. Moved to Codeberg

mmpdb. A package to identify matched molecular pairs and use them to predict property changes.

molgrep. CLI to search molecules with substructures matches

rdkitcffi. Rust wrapper for the RDKit using CFFI

nushell. A new type of shell

rustworkx. A high performance Python graph library implemented in Rust.

ProgrammingProjects. C++ Programming Tutorial in Chemistry

libscientific. Libscientific is a C framework for multivariate and other statistical analysis

Cosmos-Tokenizer. A suite of image and video neural tokenizers

XCube. [CVPR 2024 Highlight] XCube: Large-Scale 3D Generative Modeling using Sparse Voxel Hierarchies

marimo. A reactive notebook for Python — run reproducible experiments, query with SQL, execute as a script, deploy as an app, and version with git. Stored as pure Python. All in a modern, AI-native editor.

molplotly. add-on to plotly which show molecule images on mouseover!

projection-conditioned-point-cloud-diffusion. Official code for "Projection-Conditioned Point Cloud Diffusion for Single-Image 3D Reconstruction" (CVPR 2023)

synflownet. A GFlowNet with a chemical synthesis action space.

biotite. A comprehensive library for computational molecular biology

cookiecutter-cms. Python-centric Cookiecutter for Molecular Computational Chemistry Packages

DeepMatrixInversion. Neural Network Matrix Inversion

rootutils. A simple python package to solve all your problems with pythonpath, work dir, file paths, module imports and environment variables.

bayesflow. A Python library for efficient Bayesian modeling with deep learning

molecular_spaces. Jupyter Notebook

nanodo. Python

pymol_viridis. Colorblind-friendly, perceptually uniform palettes for pymol

medchem. Molecular filtering for drug discovery.

dspy. DSPy: The framework for programming—not prompting—language models

syntheseus. Package for Retrosynthetic Planning

autotrain-advanced. 🤗 AutoTrain Advanced

LangSim. Application of Large Language Models (LLM) for computational materials science - visit jan-janssen.com/LangSim

practical_cheminformatics_tutorials. Practical Cheminformatics Tutorials

pyro. Deep universal probabilistic programming with Python and PyTorch

lerobot. 🤗 LeRobot: Making AI for Robotics more accessible with end-to-end learning

lectures. Material for gpu-mode lectures

annotated_deep_learning_paper_implementations. 🧑‍🏫 60+ Implementations/tutorials of deep learning papers with side-by-side notes 📝; including transformers (original, xl, switch, feedback, vit, ...), optimizers (adam, adabelief, sophia, ...), gans(cyclegan, stylegan2, ...), 🎮 reinforcement learning (ppo, dqn), capsnet, distillation, ... 🧠

uv. An extremely fast Python package and project manager, written in Rust.

lightning-thunder. PyTorch compiler that accelerates training and inference. Get built-in optimizations for performance, memory, parallelism, and easily write your own.

fiftyone. Refine high-quality datasets and visual AI models

Qwen-VL. The official repo of Qwen-VL (通义千问-VL) chat & pretrained large vision language model proposed by Alibaba Cloud.

ImageBind. ImageBind One Embedding Space to Bind Them All

tuning_playbook. A playbook for systematically maximizing the performance of deep learning models.